“Idea stealing”- does it affect scientific innovation and creativity?

It is very interesting to note that “stealing others idea’ is a widely accepted common practice in research, both in academic and industrial laboratories. In a society where stealing, even petty things, is considered as a punishable crime, people steal ideas openly, without any hesitation, in academic and industrial organizations. Stealing expressions or ideas from other’s speech or articles (plagiarism) is considered wrong and can be punishable too. So many people have lost their reputation and career as a result of our harsh approach on preventing plagiarism. Conversely, people get away with stealing others ideas in a research set-up for making money or for attaining power or position. We all agree that this is wrong and unethical; however, most of the researchers may feel helpless and do not how to address this issue without jeopardizing their current and future job security. In this blog, we will discuss the direct scientific and socio-economic impact of “idea stealing” in a scientific research environment, particularly in industrial R&D laboratories. Read more: http://www.sciclips.com/sciclips/blogArticle.do?id=1016&blog=

Recent Biomarker Research Highlights

1. Protein chip for diagnosis of sepsis
2. c-myb alternative splicing variants as potential biomarkers of leukemia
3. Biomarkers for the diagnosis of anorchia
4. Biomarkers for assessing therapeutic efficacy in patients with Hutchinson-Gilford progeria syndrome
5. IGF-1 as a biomarker of abdominal aortic aneurysms
6. Serum N-glycans as colorectal cancer biomarkers
7. Gene markers associated with NEO personality traits
8. Human intelligence is highly heritable and polygenic
9. Mannose 6-phosphate as a biomarker for the diagnosis of mucolipidosis Type II
10. ME-2 antigen as a biomarker for the diagnosis of endometriosis
11. Uromodulin and Kinins as biomarkers for the diagnosis of chronic allograft dysfunction
12. Micronucleus as a biomarker to screen women who are at risk of developing cervical cancer
13. Biomarkers of neuronal ceroid lipofuscinosis
14. Biomarkers to identify CKD patients in whom sodium targeting can improve blood pressure and proteinuria
15. Mitochondrial DNA copy number as a possible biomarker of pancreatic cancer
16. Biomarkers associated with higher risk of progression in lacunar strokes
17. XRCC1 SNP biomarker to predict genetic susceptibility for papillary thyroid carcinoma
18. HESRG as a specific biomarker for intracranial germinoma and embryonal carcinoma
19. Predictive biomarkers of efavirenz-based HAART-induced liver injury in HIV patients
20. Biomarker for predicting the development of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
Details: http://www.sciclips.com/sciclips/drug-discovery-news.do

Recent Biomarker Patents

1. Gene expression biomarkers for the detection of acute allograft rejection

2. Method for sequencing peptides and proteins using metastable-activated dissociation mass spectrometry

3. Epigenetic biomarkers for cervical cancer

4. Phospho-cErbB2 as a predictive biomarker for erbB2-directed cancer therapy

5. Metabolomic biomarkers for the diagnosis of prostate cancer relapse

6. Surrogate biomarkers for monitoring the efficacy of specific pharmacological chaperone in Pompe disease

7. miRNA biomarkers for diagnosing myelodysplastic disease syndrome

8. ADAM 12 as a urinary biomarker of bladder cancer

9. Metabolomic biomarkers for the diagnosis of heart failure

10. Biomarker for diagnosing the risk of developing cardiovascular diseases

11. Protein biomarkers for the diagnosis of schizophrenia

12. Noninvasive prenatal diagnosis of fetal aneuploidies using maternal blood

13. Lysyl tRNA synthetase (KRS) and laminin receptor (67LR) as biomarkers of lung cancer or breast cancer

14. Biomarkers for the diagnosis of B cell chronic lymphocytic leukemia (B-CLL)

15. A method of detecting circulating tumor cells (CTCs)

16. Autoantibody biomarkers of the cancer of gingivo-buccal complex

17. Direct quantitation of glycated hemoglobin in blood samples

18. Urinary Cyr61 protein as a diagnostic biomarker of breast cancer or ovarian cancer

19. Gene expression biomarkers for the prognosis in severe sepsis

20. Biomarker genes for the diagnosis of scleroderma

21. MicroRNA biomarkers for the prognosis of lung cancer

22. Biomarkers of systemic sclerosis

23. Biomarkers for diagnosing a form of lower back pain (LBP)

24. Biomarkers for the diagnosis of Kawasaki disease

Details: http://www.sciclips.com/sciclips/biomarker-news.do

Recent drug discovery patents

1. Glycine B as drug target for the treatment of neurological disorders

2. Synthetic antigen based malaria vaccine

3. Combination of therapy for the treatment of schizophrenia and bipolar disorder

4. Taxol for the treatment of atherosclerosis

5. MicroRNAs as drug targets for the treatment of chronic, non-healing wounds and acute wounds

6. MicroRNAs for the treatment of age-related macular degeneration or proliferative vitreal retinopathy

7. PYY peptide analogues for the treatment of diabetes and obesity

8. Neuregulin for the treatment of myocardial ischemia reperfusion injury

9. A1 adenosine receptor as drug target for the treatment of renal impairment

10. IL-7 receptor (CD127) as a drug target for the treatment of multiple sclerosis

11. Bifunctional inhibitors of DNA replication and repair proteins for the treatment of cancer

12. Inhibitors of SI00 protein binding interactions for the treatment of cancer

13. Low-affinity nerve growth factor receptor (NGFR) as a marker for differentiation in muscle stem cells

14. Differentiation of MSCs from pluripotent cells using activin and TGF-beta inhibitors

15. Depletion of pluripotent stem cells from a mixed cell population

16. Placental stem cells for the treatment of bone cancer

17. Isolation of multipotent cardiovascular progenitors from stem cells using cell surface markers

18. HSS1 and HSM1 proteins for the treatment of brain cancers

19. Prominin-1 derived peptides as angiogenesis agents

20. Peptide based combination therapy for obesity and diabetes

21. PDE1 inhibitor to treat pathological cardiac remodeling and heart failure

22. GPR119 G protein-coupled receptor modulators for the treatment of diabetes

23. Low molecular weight CDK inhibitor for the treatment of glioblastoma

24. Pyridine and pyrimidine based compounds as inhibitors of Wnt signaling for the treatment of cancer

25. Anti-cancer vaccine DNL complexes using dock-and-lock technology

26. DII4 as drug target of autoimmune diseases

27. C-peptide for treating erectile dysfunction associated with diabetes

28. Src family kinase /Nef protein interaction as a drug target for HIV-I

29. Cyclic tetrapeptide kappa opioid receptor (KOR) antagonists for the treatment of drug addiction

30. Combination therapy for cancer using oligonucleotide inhibitors of IGFBPs and clusterin

31. Wax synthase activity of a MTTGS as a drug target for tuberculosis

32. Nkx3.2 protein as a therapeutic drug target of osteoarthritis

33. Oligonucletode based inhibitors of PWWP domain protein for the treatment of neuroblastoma

Details: http://www.sciclips.com/sciclips/drug-discovery-news.do